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Research Article
Revised

Gaining insights into a funding portfolio through publication tracking

[version 2; peer review: 1 approved, 1 approved with reservations]
PUBLISHED 06 Oct 2025
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Abstract

Background

The National Institute for Health and Care Research (NIHR) is the UK’s biggest funder for health and social care research, funded by the Department of Health and Social Care (DHSC). The NIHR infrastructure provides research expertise, specialist facilities, a research delivery workforce and support services, all of which help to support and deliver the research we fund, and research funded by others. The NIHR is committed to maximising the impact of the research we support and fund 1 and therefore, it is crucial for the organisation to understand the mechanisms for the movement of research between these different pieces of research infrastructure and pathways to impact on the health and wealth of the nation. The aim of this article is to share our approach to developing an understanding of pathways to impact, enablers and barriers and lessons learnt.

Methods

We used publications reported to us by our infrastructure as receiving infrastructure support and forward and backward citation analysis to trace infrastructure support for REF 2021 impact case studies and research that has had an impact on policy. We used these data to develop impact case studies for NIHR infrastructure.

Results

Of the 6,361 REF impact case studies that are publicly available, the NIHR infrastructure has supported 327 of which 59 are supported by more than one scheme. Through our forward and backward citation analysis we have also developed impact case studies in the following NIHR priority areas:

  • Reducing health inequalities

  • Digital health

  • Artificial intelligence

  • Workforce resilience

Conclusions

The use of forward and backward citation analysis can also help research funders to understand how research is moving between different parts of their funding portfolios, pathways to impact and any gaps and opportunities. However, this comes with some challenges which need mitigation.

Plain Language Summary

Plain English Summary

The National Institute of Health and Care research (NIHR) is funded by the Department of Health and Social Care. It funds a £600M/year portoflio of infrastructure which provided support and a delivery workforce for experimental and clinical research in England. NIHR infrastructure report to the NIHR on an annual basis and one of the reporting requirements is a list of research publications that have been supported by the infrastructure. Using these it is possible to trace which research publications have either been cited by NIHR infrastructure supported research publications and which research publications cite NIHR infrastructure supported publications. This helps the NIHR to understand what types of research and within its portfolio and how the research moves within the health and care ecosystem to have an impact on the real world. This is important for the NIHR to be able to demonstrate the value of publicly funded research and fulfil its mission of improving the health and wealth of the nation. In this article we describe our methods for doing this to enable other funders to be able to learn from our experience.

Keywords

funding, portfolio, publications, citations, case studies, Research Excellence Framework

Revised Amendments from Version 1

In line with reviewer comments, we have provided an additional figure to show the flow of our citation analysis. We have provided additional detail on our case study development and validation process, including our researcher interviews. We have also provided additional clarity on the areas of strength identified and discussed in the discussion section. Finally, we have addressed minor typos, grammar issues and fixed incorrect references.

See the authors' detailed response to the review by Erik Canton
See the authors' detailed response to the review by Josie Coburn

Introduction

The National Institute for Health and Care Research (NIHR) is the UK’s biggest funder for health and social care research, funded by the Department of Health and Social Care (DHSC). The NIHR invests approximately £600M/year in research infrastructure2, which provides a platform to enable early stage and applied health research. The NIHR infrastructure provides research expertise, specialist facilities, a research delivery workforce and support services, all of which help to support and deliver the research we fund, and research funded by others.

The NIHR’s research delivery infrastructure is focused on supporting clinical trial delivery, whereas, its research infrastructure portfolio is made up of four schemes which span the innovation pathway from early phase experimental and research through to clinical evaluation, implementation and adoption and spread. Our Biomedical Research Centres (BRCs)3 translate discovery research into clinical settings. They take innovations or interventions that have evidence of proof of concept and study translatability into NHS settings. Our Patient Safety Research Collaborations (PSRCs, and their precursor)4 evaluate patient safety for innovations and interventions for NHS use. The HealthTech Research Centres (HRCs, and their precursors)5 evaluate health technology based interventions for NHS use and our Applied Health and Social Care Collaborations (ARCs, and their precursor)6 focus on implementation science and evaluations in real-world settings to help build the evidence-base for scale up and roll-out within NHS settings.

The NIHR is committed to maximising the impact of the research we support and fund1 and therefore, it is crucial for the organisation to understand the mechanisms for the movement of research between these different pieces of research infrastructure and pathways to impact on the health and wealth of the nation. NIHR infrastructure funding can be used towards pump priming funding. However, it is largely aimed at supporting research and research delivery workforce roles which enable research to take place and career development. The research that is supported by NIHR infrastructure is typically either exclusively or partly funded by external funding. This makes attributing the impact of research projects to NIHR infrastructure difficult due to a lack of a direct, linear relationship between the infrastructure funding and specific projects in the majority of cases.

The Research Excellence Framework (REF)7 is a crucial data source for impact case studies for the NIHR because it is the UK’s exercise for evaluating the quality of research produced by Higher Education Institutes (HEIs), approximately every 7 years. HEIs produce independently evidenced impact case studies which have been underpinned by excellent research from the submitting HEI. Impact case studies that do not contain commercially or otherwise sensitive information are made publicly available at the end of the assessment exercise. The last REF exercise that had been conducted at the time of writing was in 2021.

The aim of this article is to share our approach to developing an understanding of pathways to impact, enablers and barriers and lessons learnt.

Research design and methods

Data sources

The REF 2021 impact case study dataset. The REF 2021 impact case study dataset was downloaded from the REF 2021 website8. At the time of download, there were 6,361 publicly available impact case studies. Each impact case study contains information on the summary of the impacts, the underpinning research, the details of the impacts and list of publications and sources of evidence of the impacts.

NIHR infrastructure publication data. Each year, NIHR infrastructure award holders submit annual reports to the NIHR. These contain information about publications that have been supported by the infrastructure. The publication data provided include a publication reference in the form of a publication citation as well as the associated Digital Object Identifiers (DOI). In some cases, Pubmed or Pubmed Central identifiers are provided instead of the DOI. Where an identifier is missing, the publication reference is used to query Pubmed to systematically source the relevant information. Publication identifiers are validated using Dimensions, Europe Pubmed Central and Pubmed.

Linking up REF data with our publication data. The list of publications section of the REF 2021 impact case studies could also be optionally used by HEIs to include information about funding for the underpinning research but we found that this option was inconsistently used across the HEIs. When used, we found that this optional element typically covered project funding for which a specific amount of funding was directly attributable to the project, which is not a feature of NIHR infrastructure funding. Therefore, we used the list of publications from the REF 2021 impact case studies to link the case studies to NIHR infrastructure support.

Additional citation analysis. Using forward and backward citation analysis9, as shown in Figure 1, we also traced the movement of research as follows:

  • From the BRCs to the ARCs, PSRCs and HRCs

  • From the PSRCs and HRCs to the ARCs

d08292d6-69b5-4f6d-bd67-82a0fd593fd8_figure1.gif

Figure 1. This is a diagrammatic representation of how we have used forward and backward citation analysis to trace the movement of research from one piece of NIHR infrastructure to another but also from NIHR infrastructure into the policy space in order to develop our impact case studies.

Backward citations provide an indication of where research has been ‘pulled’ into the NIHR infrastructure from and forward citations provide an indication of where research from the NIHR infrastructure has been ‘pushed’ along the innovation pathway into further research or real-world settings.

We then ran ARC publications that had been underpinned by BRCs, PSRCs or HRCs through Overton10 to search for policy citations. The policy papers were manually coded to the following NIHR priority areas of interest:

  • Reducing health inequalities

  • Digital health

  • Artificial intelligence

  • Workforce resilience

NIHR case study development and validation. The REF 2021 impact case studies were coded to NIHR priority areas based on key word searches, for example ‘health inequalities’, ‘digital’, ‘digital health’, ‘artificial intelligence’, ‘workforce’ within the titles, impact summaries and details of the impact section. These were manually cross-checked. Case studies in our priority areas that had been supported by collaborative working across more than one infrastructure scheme were then selected for adaptation to create NIHR impact case studies to help us to understand how different pieces of infrastructure work together. We also developed impact cases studies in the four areas of policy interest based on ‘bodies of work’ involving multi-disciplinary researchers and research teams from different parts of NIHR research infrastructure. Semi-structured interviews were conducted with researchers or representatives of research teams and thematically analysed using inductive theming in order to understand how different pieces of NIHR infrastructure work together, enablers, barriers and challenges and evidence of impact. Any impact claims were validated using data sources that were independent of the researchers involved.

Patient and Public Involvement. Patients and the public were not involved in this research because it is not health research. The authors of this article work for the NIHR and have conducted this research on research to understand what is funded and supported by the NIHR, to provide transparency and accountability for the public money that the NIHR spends on research.

Results and discussion

NIHR infrastructure support for REF case studies

Of the 6,361 REF impact case studies that are publicly available, the NIHR infrastructure has supported 327 of which 59 are supported by more than one scheme. Figure 2 shows the numbers for how many REF impact case studies were supported by each type of NIHR infrastructure and where impact case studies were supported by just one infrastructure scheme. Figure 3 breaks the total number of REF impact case studies supported by NIHR infrastructure i.e 327 into the different types of impact, as classified by the REF dataset.

d08292d6-69b5-4f6d-bd67-82a0fd593fd8_figure2.gif

Figure 2.

This graph shows (a) how many REF impact case studies have been supported by each type of NIHR infrastructure and (b) how many REF impact case studies have been supported by just one infrastructure scheme.

d08292d6-69b5-4f6d-bd67-82a0fd593fd8_figure3.gif

Figure 3. This graph shows the total number of REF impact cases that have been supported by the NIHR infrastructure, broken down by impact type.

Insights from researcher interviews

The interviews that formed part of the case study development process explored how different pieces of NIHR infrastructure work together, enablers and barriers for impact. This revealed five areas of strength in terms of how NIHR infrastructure delivers impact and areas for future work to better understand some of these mechanisms.

The first is strategic partnerships and collaborations between different pieces of NIHR infrastructure and how these help to move projects down the innovation pathway11. An example of this is a strategic partnership between the MindTech HRC12 and the SLaM BRC13. The BRC brings expertise in the early stage investigation of mechanisms that underpin new interventions or technologies. The HRC brings expertise in the evaluation of these interventions or technologies in NHS settings. By working together, these two pieces of infrastructure can ensure that minimal time and money is lost in developing products that won’t work in the NHS. This way of working is also called ‘fast failure’14 and enables the movement of interventions from bench to bedside quicker than the typical 10–15 year time lag between research and impact15.

The ability to embed research in the NHS is a key strength of NIHR infrastructure. An example of this is research16 by the Yorkshire and Humber PSRC which looked at the effects of wellbeing and burnout of healthcare professionals on patient safety. Prior to this research, the interest in NHS workforce resilience was primarily on retention and skills rather than wellbeing. The direct involvement of clinical and academic staff in research projects also means that clinical data that are not routinely collected can be monitored to help understand unmet needs but also build the evidence base for novel interventions.

The case study development process revealed close working relationships between the NIHR infrastructure, particularly the ARCs, and commissioners through the Health Innovation Networks (HINs)17. The HINs support the evaluation and implementation of innovations in the NHS to address specific challenges and foster economic growth. This allows NIHR infrastructure to build the evidence base for and push new interventions and technologies into the NHS but also pull ideas and interventions from the HINs to evaluate in various ways. An example of this is ARC North Thames which evaluated the benefits of co-locating welfare advice services in GP settings, demonstrating significant improvements in patient mental health and well-being, reaching those most in need and supporting healthcare staff. This directly led to services being retained in primary care settings in specific parts of England and roll-out nationally in Scotland18. Understanding the push/pull mechanisms between the NIHR infrastructure and the HINs and wider health and care system is an area for future work.

The next area of strength is core funding. NIHR infrastructure contracts tend to be at least five years in length which means that infrastructure centres have well developed patient and public involvement and engagement (PPIE)19, business development, and intellectual property management functions which enable early and seamless input but also the ability to quickly pivot towards addressing new or emerging health and care system needs. In the absence of these, external funding would need to be sought for specific projects which could cause administrative delays or lead to the ‘death’ of projects considered high risk or not in line with specific funder priorities. The infrastructure also has established mechanisms for sharing and linking with various databases and sources which enrich the research. Another area for future work is understanding why this ‘valley of death’20 exists for projects and what additional support can be provided to help.

The NIHR infrastructure supports PhD students, post-docs and other researchers from a range of disciplines and at different career stages, recruited to support specific projects. Core funding enables a greatly reduced reliance on external, short-term, precarious funding21 to attract and retain research talent. The buy-out of their time allows them to develop and explore new ideas, sometimes using seed funding from the infrastructure, to get them to a stage where external funding can be sought. Early career researchers also have opportunities to co-lead various initiatives in the PPIE or knowledge mobilisation space, for example, which helps with career development for succession planning within the infrastructure. The NIHR Academy22 provides training and support to health and care researchers at all stages of their careers to build national health and care research capacity and capability. Evaluating our capacity building programmes helps us to understand their value and further develop them to meet the dynamic needs of our workforce.

The interviews also revealed a specific need for more join up across the social care system which is fragmented due to the fact that is it made up of several private organisations, commissioned to deliver NHS or community care services. This poses a challenge for adoption, implementation and downstream impacts on patients, due to the amount of time and costs of working with multiple stakeholders across the care system. Targeted funding to support researchers with policy- or implementation-ready research findings to work with multiple companies within the care system could help with this.

Conclusions

Publications are typically used to track what’s in a funding portfolio in terms of research areas but also reach of research through various altmetrics. The use of forward and backward citation analysis can also help research funders to understand how research is moving between different parts of their funding portfolios, pathways to impact and any gaps and opportunities. However, this does come with some challenges around data quality and timeliness, for example, which need mitigation.

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VERSION 2 PUBLISHED 22 Jul 2025
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Suri-Ogilvie R, Hicks S, Capostagno D et al. Gaining insights into a funding portfolio through publication tracking [version 2; peer review: 1 approved, 1 approved with reservations]. NIHR Open Res 2025, 5:62 (https://doi.org/10.3310/nihropenres.14022.2)
NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article.
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ApprovedThe paper is scientifically sound in its current form and only minor, if any, improvements are suggested
Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit.
Not approvedFundamental flaws in the paper seriously undermine the findings and conclusions
Version 2
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PUBLISHED 06 Oct 2025
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Reviewer Report 31 Oct 2025
Josie Coburn, SPRU - Science Policy Research Unit, University of Sussex, Brighton, England, UK 
Approved
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Thank you for updating this article. I think the clarity has improved and I'm happy with the quality.

I think one more minor typo has been introduced in the editing in the introduction: "from early phase experimental ... Continue reading
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Coburn J. Reviewer Report For: Gaining insights into a funding portfolio through publication tracking [version 2; peer review: 1 approved, 1 approved with reservations]. NIHR Open Res 2025, 5:62 (https://doi.org/10.3310/nihropenres.15363.r37563)
NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article.
Version 1
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PUBLISHED 22 Jul 2025
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Reviewer Report 03 Sep 2025
Josie Coburn, SPRU - Science Policy Research Unit, University of Sussex, Brighton, England, UK 
Approved with Reservations
VIEWS 17
This paper provides a very interesting investigation of the impacts of UK National Institute for Health and Care Research (NIHR) infrastructure funding by linking publications cited by UK Research Excellence Framework (REF) impact case studies with those supported by NIHR ... Continue reading
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CITE
HOW TO CITE THIS REPORT
Coburn J. Reviewer Report For: Gaining insights into a funding portfolio through publication tracking [version 2; peer review: 1 approved, 1 approved with reservations]. NIHR Open Res 2025, 5:62 (https://doi.org/10.3310/nihropenres.15250.r36488)
NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article.
  • Author Response 06 Oct 2025
    Reetika Suri-Ogilvie, NIHR Infrastructure, National Institute of Health and Care Research, London, UK
    06 Oct 2025
    Author Response
    We would like to thank the reviewer for their time taken to provide feedback on our manuscript and for their positive and constructive comments.

    We have added a bit ... Continue reading
COMMENTS ON THIS REPORT
  • Author Response 06 Oct 2025
    Reetika Suri-Ogilvie, NIHR Infrastructure, National Institute of Health and Care Research, London, UK
    06 Oct 2025
    Author Response
    We would like to thank the reviewer for their time taken to provide feedback on our manuscript and for their positive and constructive comments.

    We have added a bit ... Continue reading
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Reviewer Report 23 Aug 2025
Erik Canton, Directorate-General for Research and Innovation, European Commission, Brussels, Belgium 
Approved with Reservations
VIEWS 21
This paper by Suri-Ogilvie et al. on "Gaining insights into a funding portfolio through publication tracking" investigates the impact of the research supported and funded by the National Institute for Health and Care (NIHR) in the UK. To maximise the ... Continue reading
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CITE
HOW TO CITE THIS REPORT
Canton E. Reviewer Report For: Gaining insights into a funding portfolio through publication tracking [version 2; peer review: 1 approved, 1 approved with reservations]. NIHR Open Res 2025, 5:62 (https://doi.org/10.3310/nihropenres.15250.r36489)
NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article.
  • Author Response 06 Oct 2025
    Reetika Suri-Ogilvie, NIHR Infrastructure, National Institute of Health and Care Research, London, UK
    06 Oct 2025
    Author Response
    We thank our reviewers for their time taken to review our work and kind and helpful comments.
    We have fixed the typos in the manuscript. We have also included a ... Continue reading
COMMENTS ON THIS REPORT
  • Author Response 06 Oct 2025
    Reetika Suri-Ogilvie, NIHR Infrastructure, National Institute of Health and Care Research, London, UK
    06 Oct 2025
    Author Response
    We thank our reviewers for their time taken to review our work and kind and helpful comments.
    We have fixed the typos in the manuscript. We have also included a ... Continue reading

Comments on this article Comments (0)

Version 2
VERSION 2 PUBLISHED 22 Jul 2025
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Alongside their report, reviewers assign a status to the article:
Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested
Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit.
Not approved - fundamental flaws in the paper seriously undermine the findings and conclusions

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